The Blood–Brain Barrier

Description

The human brain is protected from bacteria and toxins, which course through the blood–stream, by a single layer of cells called the blood–brain barrier. These data come from an experiment (on rats, which process a similar barrier) to study a method of disrupting the barrier by infusing a solution of concentrated sugars.

Usage

case1102

Format

A data frame with 34 observations on the following 9 variables.

Brain

Brain tumor count (per gm)

Liver

Liver count (per gm)

Time

Sacrifice time (in hours)

Treat

Treatment received

Days

Days post inoculation

Sex

Sex of the rat

Weight

Initial weight (in grams)

Loss

Weight loss (in grams)

Tumor

Tumor weight (in 10^(-4) grams)

Source

Ramsey, F.L. and Schafer, D.W. (2002). The Statistical Sleuth: A Course in Methods of Data Analysis (2nd ed), Duxbury.

Examples

str(case1102)

plot(Brain/Liver ~ Time, case1102, log="xy", pch=ifelse(Treat=="BD", 19,21))
legend(10,0.1, pch=c(19,21), c("Saline control", "Barrier disruption"))